During the Playstation 4 reveal event, Sucker Punch, developers behind the Infamous series have shown off their upcoming Playstation 4 exclusive, Infamous: Second Son.
Second Son takes place seven years after the events of Infamous 2. It will happen in Seattle, a real city as opposed to Empire City which is modeled after New York. The protagonist is Delsin Rowe, a 24 year old underachiever. Cole Macgrath's powers were electricity, Delsin Rowe's powers will revolve around smoke.
We can assume from the atmosphere the presentation at the event put us in, that Seattle is now a police state and Delsin doesn't like that fact. Like the previous installements, the choices you make will determine the path of the story.